Clinical science has been developed by the linear scheme of causation (one cause - one disease phenotype). A linear scheme of causation is useful for infectious diseases and monogenic diseases. However, this scheme generates combinatorial explosion against multifactorial disorders. To overcome, we are going to develop a information geometry based reasoning technology that consist from multidimentional descriptors for multi-omics data and dimensionality reduction technology. These technologies will be applied to development of personalized prediction algorithm for multifactorial disorders. Developed technologies will be available for medical institution and industry.
Program Director MIH,
Executive Director RIKEN
Deputy Program Director, MIH
Senior Researcher, Sony Computer Science Laboratories, Inc.